Glycoengineering bioconjugate vaccines, therapeutics, and diagnostics in E. coli

Bioconjugate Therapeutics: Current Progress and Future Perspective.

Chikungunya: vaccines and therapeutics

Chikungunya virus (CHIKV) has come to prominence as a global, re-emerging pathogen over the last two decades, progressing from sporadic, remote outbreaks to worldwide explosive epidemics. From contained, though considerable, outbreaks in the southern Indian Ocean, parts of South America and the Caribbean, CHIKV continues to be a significant pathogen in Southeast Asia and India. CHIKV circulates...

Microarray profiling of antiviral antibodies for the development of diagnostics, vaccines, and therapeutics.

Multiplex analysis of antiviral antibody (Ab) responses provides a potentially powerful strategy for viral diagnosis, prognostication, and development of vaccines and prophylactic Abs. In the coming years, advancements in proteomic technologies will provide even more robust methods to characterize antiviral Ab responses. Biomedical researchers will be faced with the exciting challenge of identi...

Gold Nanoparticles in Molecular Diagnostics and Therapeutics

Multifunctional nanoparticles, which incorporate diagnostic (quantum dots, magnetic, metallic, polymeric and silica nanoparticles) and/or therapeutic (magnetic and metallic nanoparticles) properties, are in the process of development. They have been used in vivo to protect the drug entity in the systemic circulation, restrict access of the drug to the chosen sites and to deliver the drug at a c...

Supramolecular Nanoparticles for Molecular Diagnostics and Therapeutics